Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Mediastinal and cervical histoplasmosis simulating malignancy

C H Zeanah, J Zusman

American Journal of Diseases of Children (1960)

|January 1, 1979

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Disruptions of working memory and inhibition mediate the association between exposure to institutionalization and symptoms of attention deficit hyperactivity disorder.

Psychological medicine·2015

Same author

Reaction.

The journal of primary prevention·2013

Same author

Addendum to debate statement.

The journal of primary prevention·2013

Same author

"No-therapy": A method of helping persons with problems.

Community mental health journal·2013

Same author

Telomere length and early severe social deprivation: linking early adversity and cellular aging.

Molecular psychiatry·2011

Same author

A relational perspective on PTSD in early childhood.

Journal of traumatic stress·2002

Same journal

Nonsteroidal anti-inflammatory drugs and gastrointestinal injury in children.

American journal of diseases of children (1960)·1993

Same journal

Picture of the month. Cutaneous leishmaniasis.

American journal of diseases of children (1960)·1993

Same journal

Pathological case of the month. Wells' syndrome.

American journal of diseases of children (1960)·1993

Same journal

Radiological case of the month. Proteus syndrome: benign angiolipomatous tumor with intraspinal extension.

American journal of diseases of children (1960)·1993

Same journal

Applicability of the Greulich and Pyle skeletal age standards to black and white children of today.

American journal of diseases of children (1960)·1993

Same journal

Maltreatment of children born to cocaine-dependent mothers.

American journal of diseases of children (1960)·1993

See all related articles

Histoplasmosis, an infectious disease, can mimic lymphoma by causing cervical and mediastinal masses in children. This case highlights the importance of considering infections in the differential diagnosis of pediatric masses.

Area of Science:

Pediatric Infectious Diseases
Medical Mycology
Diagnostic Imaging

Background:

Anterior mediastinal masses in children can present diagnostic challenges.
Differential diagnosis often includes neoplastic and infectious etiologies.
Histoplasma capsulatum is a fungal pathogen endemic to certain regions.

Observation:

A 12-year-old boy presented with a purulent cervical mass and an anterior mediastinal mass.
Imaging revealed masses in both the anterior cervical region and anterior mediastinum.
Cultures and histopathology confirmed Histoplasma capsulatum as the causative agent.

Findings:

The cervical mass was likely a manifestation of disseminated histoplasmosis.
The pattern of involvement suggested spread along pathways similar to Hodgkin's disease.

Related Experiment Videos

Infectious histoplasmosis presented with symptoms mimicking malignancy.

Implications:

Histoplasmosis should be considered in the differential diagnosis of pediatric anterior mediastinal and cervical masses.
This case underscores the importance of thorough infectious disease workup for pediatric masses.
Recognizing infectious mimics of malignancy is crucial for appropriate patient management and treatment.