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Infantile hepatic haemangioendothelioma
1Radiology Department, Mater Children's Public Hospital, South Brisbane, Queensland, Australia.
Australasian Radiology
|May 1, 1995
Summary
Infantile hepatic haemangioendotheliomas can spontaneously regress. However, some cases present severe complications like cardiac failure, necessitating prompt medical intervention.
Area of Science:
- Pediatric Oncology
- Vascular Anomalies
- Diagnostic Imaging
Background:
- Infantile hepatic haemangioendotheliomas (IHH) are the most common benign liver tumors in infants.
- While often self-limiting, IHH can lead to significant morbidity and mortality.
Observation:
- This study describes three cases of IHH, detailing their clinical presentation and natural history.
- Two cases showed spontaneous tumor regression without complications.
- One case presented with life-threatening complications including cardiac failure, thrombocytopenia, and disseminated intravascular coagulation.
Findings:
- Imaging modalities such as plain films, ultrasound, computed tomography, and angiograms were utilized to assess the tumors.
- Pathological findings were described for two of the cases, providing histological insights.
- The diverse clinical spectrum of IHH, from benign regression to severe complications, is highlighted.
Implications:
- Early recognition and monitoring of IHH are crucial for timely management.
- Understanding the natural history aids in differentiating benign from complicated cases.
- This case series underscores the importance of multidisciplinary care for infants with complex hepatic haemangioendotheliomas.