Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pediatric arsenic ingestion

N M Cullen1, L R Wolf, D St Clair

  • 1Department of Emergency Medicine, Wright State University School of Medicine, Dayton, OH 45429, USA.

The American Journal of Emergency Medicine
|July 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Differential antibody responses to gliadin-derived indigestible peptides in patients with schizophrenia.

Translational psychiatry·2017
Same author

Inhibition of the integrin/FAK signaling axis and c-Myc synergistically disrupts ovarian cancer malignancy.

Oncogenesis·2017
Same author

Expression analysis in a rat psychosis model identifies novel candidate genes validated in a large case-control sample of schizophrenia.

Translational psychiatry·2015
Same author

Bridging the translational divide: identical cognitive touchscreen testing in mice and humans carrying mutations in a disease-relevant homologous gene.

Scientific reports·2015
Same author

Latexin sensitizes leukemogenic cells to gamma-irradiation-induced cell-cycle arrest and cell death through Rps3 pathway.

Cell death & disease·2014
Same author

DISC1 as a genetic risk factor for schizophrenia and related major mental illness: response to Sullivan.

Molecular psychiatry·2014
Same journal

PECARN use and implementation barriers among Canadian emergency physicians: An exploratory national survey.

The American journal of emergency medicine·2026
Same journal

Isolated angioedema in the emergency department: rarely an allergic reaction.

The American journal of emergency medicine·2026
Same journal

Diagnostic accuracy of emergency department triage systems for predicting clinical severity: A systematic review and meta-analysis of five-level triage scales.

The American journal of emergency medicine·2026
Same journal

Methanol toxicity from inhalational abuse of a methyl acetate-containing nail polish remover.

The American journal of emergency medicine·2026
Same journal

Regarding strategies, feasibility of implementations and results of HIV screening in emergency departments.

The American journal of emergency medicine·2026
Same journal

Rocuronium dosing for rapid sequence intubation: A retrospective analysis in ED and ICU settings.

The American journal of emergency medicine·2026
See all related articles

This case report details a rare pediatric acute arsenic poisoning successfully treated with British antilewisite (BAL), D-penicillamine (DP), and dimercaptosuccinic acid (DMSA), showing faster arsenic excretion in children.

Area of Science:

  • Toxicology
  • Pediatric Medicine
  • Environmental Health

Background:

  • Acute arsenic toxicity is uncommon, particularly in pediatric populations.
  • Recent literature lacks documented pediatric cases of acute arsenic poisoning.

Observation:

  • A 22-month-old girl ingested sodium arsenate, presenting with immediate gastrointestinal distress and lethargy.
  • Initial treatment included gastric lavage and British antilewisite (BAL).
  • Subsequent treatment involved D-penicillamine (DP) and dimercaptosuccinic acid (DMSA).

Findings:

  • The patient showed rapid improvement after BAL administration.
  • Urine arsenic levels were significantly elevated initially (4,880 µg/L) but decreased with chelation therapy.
  • Dimercaptosuccinic acid (DMSA) accelerated arsenic excretion, with a half-life of approximately 2.5 days, faster than in adults.

Related Experiment Videos

Implications:

  • This case highlights effective chelation strategies for pediatric acute arsenic poisoning.
  • The findings suggest that children may excrete arsenic more rapidly than adults when treated with chelating agents.
  • Further research into pediatric arsenic excretion kinetics and long-term outcomes is warranted.