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An autopsied case of T-cell rich B-cell lymphoma with general involvement
1Department of Internal Medicine, Yamagata Prefectural Kahoku Hospital.
Internal Medicine (Tokyo, Japan)
|April 1, 1995
Abstract:
Autoptic findings of a 77-year-old man with T-cell-rich B-cell lymphoma (TCRBCL) showed predominant infiltration of reactive T-cells with a minority population of neoplastic B-cells in liver, spleen, pancreas, adrenal gland, stomach, small intestine and heart, as well as, lymph node. DNA studies demonstrated dual rearrangement in the T-cell receptor beta (TCR beta), immunoglobulin heavy chain J region (IgJH) and kappa light chain J region (IgJ kappa) genes.