Juvenile-onset pancreatic diabetes to whom a healthy infant was born
Related Experiment Video
Updated: Sep 30, 2026

Isolation of Human Islets from Partially Pancreatectomized Patients
Published on: July 30, 2011
1Department of Gastroenterology, National Kyushu Cancer Center, Fukuoka.
Insights
This report details a rare pregnancy and successful vaginal birth in a patient with diabetes secondary to chronic pancreatitis. Effective blood glucose management and dietary adjustments were key to a healthy outcome.
Area of Science:
- Endocrinology
- Gastroenterology
- Reproductive Medicine
Background:
- A patient diagnosed with chronic pancreatitis at 16, likely due to hyperlipemia, developed secondary diabetes and pancreatic calcification three years later.
- The patient achieved good glycemic control with self-monitoring and multiple daily insulin injections prior to pregnancy.
Observation:
- Pregnancy occurred at age 23 in a patient with well-controlled diabetes secondary to chronic pancreatitis.
- Management involved a slight increase in insulin dosage and adherence to a low-fat diet with digestive enzyme supplementation.
Findings:
- The patient experienced a successful transvaginal delivery.
- No acute exacerbation of chronic pancreatitis occurred during the pregnancy.
Implications:
- This case highlights the feasibility of managing pregnancy in patients with complex endocrine and gastrointestinal conditions.
- It underscores the importance of multidisciplinary care, including dietary management and insulin therapy, for successful pregnancy outcomes in such cases.
Abstract:
A rare case of pregnancy and successful transvaginal delivery in secondary diabetes due to chronic pancreatitis is reported. At the age of 16 the patient was diagnosed as having chronic pancreatitis probably caused by hyperlipemia. Three years later diabetes and calcification of the pancreas was found. Blood glucose was well controlled using both self-monitoring of blood glucose and multiple subcutaneous insulin injection just before she became pregnant at age 23. The dose of insulin was slightly increased and no acute exacerbation of pancreatitis occurred during pregnancy, partly due to an appropriate low fat diet with digestive enzyme preparations.
Related Concept Videos
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Diabetes Mellitus: Type 2 and Gestational
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Type I Diabetes I: Introduction
Type I Diabetes II: Pathophysiology
Type I Diabetes III: Clinical Manifestations

