Strength of anterior vertebral screw fixation in relationship to bone mineral density

A biomechanical study was performed to investigate the relationship among the pullout strength of anterior vertebral screw fixation, bone mineral density (BMD) of the vertebral body, screw insertion torque, and width of the vertebral body. BMD was measured using a dual energy x-ray absorptiometry unit. Screw insertion torque and width of the lumbar vertebrae were also measured before the pullout test. Pullout strength was significantly correlated with BMD (r = 0.85) and screw insertion torque (r = 0.47), but not with width of the vertebral body. Multiple regression analyses demonstrated better correlation between pullout strength and the other parameters (r = 0.886). A stepwise regression analysis showed that BMD is the most significant predictor of the pullout strength followed by width of the vertebral body, whereas screw insertion torque is not a significant predictor. Furthermore, the mean pullout strength of the grade I osteoporosis group was significantly greater than that of grade II or III osteoporosis group.