Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Outcome after right middle lobe syndrome

K De Boeck1, T Willems, D Van Gysel

  • 1Department of Pediatrics, Leuven (Belgium) University Hospital.

Chest
|July 1, 1995
PubMed
Summary

Children diagnosed with right middle lobe syndrome (RMLS) may experience long-term respiratory issues, including asthma and bronchiectasis. Early diagnosis of RMLS in childhood is linked to poorer pulmonary outcomes later in life.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

ECFS standards of care on CFTR-related disorders: Identification and care of the disorders.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society·2024
Same author

ECFS standards of care on CFTR-related disorders: Towards a comprehensive program for affected individuals.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society·2024
Same author

Assessing the trophic ecology and migration on the exposure of cape petrels and Wilson's storm petrels from Antarctica to perfluoroalkylated substances, trace and major elements.

Environmental research·2023
Same author

ECFS standards of care on CFTR-related disorders: Updated diagnostic criteria.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society·2022
Same author

Coordination pattern and variability in a flexion movement control test used in clinical assessment.

Studies in health technology and informatics·2021
Same author

Assessment of three-dimensional movement of the spine and pelvis during routine clinical assessment.

Studies in health technology and informatics·2021

Area of Science:

  • Pediatric Pulmonology
  • Respiratory Medicine
  • Childhood Lung Disease

Background:

  • Long-term pulmonary outcomes of childhood right middle lobe syndrome (RMLS) are not well-established.
  • RMLS is characterized by persistent atelectasis of the right middle lobe.

Purpose of the Study:

  • To evaluate the long-term pulmonary consequences of RMLS diagnosed in early childhood.
  • To identify risk factors associated with persistent respiratory problems after RMLS.

Main Methods:

  • A cohort of 17 children diagnosed with RMLS in early childhood was followed up.
  • Pulmonary function tests (PFTs), including spirometry and methacholine challenge tests, were performed.
  • Radiographic findings and clinical symptoms were assessed at follow-up.

Related Experiment Videos

Main Results:

  • Five of 17 children (29%) experienced ongoing respiratory problems, including asthma and bronchiectasis.
  • Patients with ongoing symptoms showed significantly lower vital capacity and FEV1 compared to controls.
  • Lower methacholine provocative dose (PD20) in symptomatic patients indicated increased airway hyperresponsiveness.
  • Younger age at initial RMLS diagnosis was associated with a trend towards poorer outcomes.

Conclusions:

  • Childhood RMLS can lead to significant long-term pulmonary sequelae, including asthma and bronchiectasis.
  • Airway hyperresponsiveness and reduced lung function are common in children with a history of RMLS.
  • Early diagnosis and intervention for RMLS may be crucial for improving long-term respiratory health.