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Related Experiment Videos

Pulsus paradoxus in asthma

C Shim, M H Williams

    Lancet (London, England)
    |March 11, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Pulsus paradoxus, a blood pressure drop during breathing, is linked to asthma severity. However, its presence doesn't always correlate with airflow obstruction due to variations in breathing patterns.

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    PULMONARY TUBERCULOSIS IN CHILDREN.

    British medical journal·2010

    Area of Science:

    • Cardiology
    • Pulmonology
    • Respiratory Medicine

    Background:

    • Pulsus paradoxus is a sign of increased respiratory effort in obstructive lung diseases.
    • Its relationship with the severity of airflow obstruction in asthma is not fully understood.

    Purpose of the Study:

    • To investigate the association between pulsus paradoxus and airflow obstruction in asthma patients.
    • To explore the influence of respiratory patterns on pulsus paradoxus.

    Main Methods:

    • Examined 93 asthma patients on 308 occasions for systolic blood pressure fluctuations during quiet breathing.
    • Measured peak expiratory flow rate (PEFR) to assess airflow obstruction.
    • Studied the effect of changing respiratory patterns on systolic fluctuation in six patients.

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    Main Results:

    • Pulsus paradoxus (≥10 mm Hg fluctuation) was present in 110/308 occasions.
    • Greater airflow obstruction was associated with pulsus paradoxus (average PEFR 33.6% predicted) compared to its absence (average PEFR 55.4% predicted).
    • Pulsus paradoxus was observed in mild obstruction and absent in severe obstruction; systolic fluctuation correlated with inspiratory flow rate.

    Conclusions:

    • The association between pulsus paradoxus and asthma severity is inconsistent.
    • Inspiratory flow rate significantly influences pulsus paradoxus, explaining its variable presence in different levels of airflow obstruction.