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Updated: Jul 31, 2026

Intracavernosal Pressure Recording to Evaluate Erectile Function in Rodents
Published on: June 6, 2018
The effect of intracavernosal injection of papaverine hydrochloride on orgasm latency
1Department of Psychiatry, Indiana University School of Medicine, Riley Hospital, Indianapolis 46202-5200, USA.
Abstract:
The research literature on the employment of various vasoactive drugs to induce penile erection has largely examined assessment and treatment techniques. One study specifically examined the duration of erection, or "orgasm latency," of the drug-induced erection. However, it did not determine the relation of this duration to pre-impotence duration. The intent of the present investigation was to make this determination. Subjects at a urology department impotence clinic were asked to estimate orgasm latency prior to impotence and with papaverine-induced erection. The mean orgasm latency prior to impotence was 9.9 minutes; with papaverine, 15 minutes. It is concluded that papaverine injection not only causes an erection but makes it last longer than naturally occurring erections.
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