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Related Experiment Videos

Metal particles and tissue changes adjacent to miniplates. A retrieval study

S Torgersen1, N R Gjerdet, E S Erichsen

  • 1Department of Dental Biomaterials, School of Dentistry, University of Bergen, Norway.

Acta Odontologica Scandinavica
|April 1, 1995
PubMed
Summary

Histomorphology and metal analysis of jaw implants revealed fibrosis and mild inflammation around both stainless steel and titanium devices. Metal particles were found in surrounding tissues, but inflammation was not solely linked to particle presence.

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Area of Science:

  • Oral and Maxillofacial Surgery
  • Biomaterials Science
  • Histopathology

Background:

  • Jaw fractures are often treated with metallic implants like miniplates and screws.
  • Understanding the long-term biological response to these implants is crucial for patient outcomes.
  • Both stainless steel and titanium are commonly used biomaterials in orthopedic and maxillofacial surgery.

Purpose of the Study:

  • To investigate the histomorphological and metal content of peri-implant soft tissue and bone surrounding stainless steel and titanium implants.
  • To assess the presence and distribution of metal particles in tissues adjacent to implants.
  • To correlate tissue reactions with the presence of metal debris.

Main Methods:

  • Histomorphological analysis using light microscopy and scanning electron microscopy (SEM).

Related Experiment Videos

  • Energy-dispersive X-ray microanalysis (EDX) for elemental composition and metal particle identification.
  • Examination of peri-implant tissues from patients with removed stainless steel (n=12) and titanium (n=3) miniplates and screws.

    • Main Results:

    • Fibrosis and mild chronic inflammation were observed in non-osseous tissues adjacent to both stainless steel and titanium implants.
    • A connective tissue collar formed between bone and screws for both materials.
    • Metal particles (5-50 microns) of stainless steel or titanium were detected in adjacent soft tissue and bone, with more particles in soft tissue.
    • Inflammatory changes were present even in areas without detectable metal impregnation.

    Conclusions:

    • Peri-implant tissues around both stainless steel and titanium implants exhibit similar histomorphological changes, including fibrosis and mild inflammation.
    • The presence of metal particles is a common finding, but mild inflammation is not exclusively associated with metal impregnation.
    • Further research is needed to fully elucidate the clinical significance of metal particle release and associated inflammatory responses.