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Related Experiment Videos

Leaching from denture base materials in vitro

H Lygre1, E Solheim, N R Gjerdet

  • 1Department of Dental Biomaterials, School of Dentistry, University of Bergen, Norway.

Acta Odontologica Scandinavica
|April 1, 1995
PubMed
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Denture base materials release organic compounds like phthalates and additives into solutions. Processing methods and materials significantly affect the type and amount of leachable substances.

Area of Science:

  • Materials Science
  • Analytical Chemistry
  • Biomaterials

Background:

  • Denture base materials are widely used in prosthodontics.
  • Leaching of organic compounds from these materials can potentially affect patient health.
  • Understanding the composition and release of these compounds is crucial for material safety.

Purpose of the Study:

  • To identify and quantify organic compounds leaching from different denture base materials.
  • To investigate the influence of processing methods and solvents on compound release.
  • To assess the variability in leachable substances among various denture base materials.

Main Methods:

  • Specimens of heat-cured and cold-cured denture base materials were prepared.
  • Materials were leached in Ringer solution and ethanol.

Related Experiment Videos

  • Leachates were analyzed using combined gas-chromatography and gas-chromatography/mass-spectrometry (GC-MS).

    • Main Results:

    • Phthalates were quantified in Ringer solution.
    • Ethanol leachates contained biphenyl, dibutyl phthalate, dicyclohexyl phthalate, phenyl benzoate, and phenyl salicylate.
    • Copper was detected in ethanol from one material.
    • Leachable compound amounts varied significantly between materials and processing conditions.

    Conclusions:

    • Denture base materials release various organic additives and degradation products.
    • Solvent type critically influences the profile of leached compounds.
    • Processing temperature impacts the initial level of leachable substances, highlighting material and processing variability.