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Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms
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Endocarditis-related cerebral aneurysms: radiologic changes with treatment

P Corr1, M Wright, L C Handler

  • 1Department of Neuroradiology, Groote Schuur Hospital, Cape Town, South Africa.

AJNR. American Journal of Neuroradiology
|April 1, 1995
PubMed
Abstract

Insights

Antibiotic therapy can resolve mycotic aneurysms, but follow-up angiography is crucial for monitoring treatment response and detecting changes in aneurysm size or new formations.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Radiology

Background:

  • Mycotic aneurysms, often linked to infective endocarditis, pose significant risks including hemorrhage and stroke.
  • Early diagnosis and effective treatment are vital for improving patient outcomes.

Purpose of the Study:

  • To evaluate the effectiveness of antibiotic therapy in treating mycotic aneurysms.
  • To correlate treatment response with patient outcomes.

Main Methods:

  • Retrospective review of clinical data, CT scans, and serial cerebral angiograms.
  • Analysis of 14 patients diagnosed with infective endocarditis and related aneurysms over a 10-year period.

Main Results:

  • Antibiotic treatment led to complete resolution of 33% of mycotic aneurysms.
  • 33% of aneurysms showed no change in size, 17% decreased, and 17% increased.
  • 50% of patients achieved complete recovery, while others experienced deficits or death from rebleeding.

Conclusions:

  • Follow-up angiography is essential for assessing antibiotic therapy response in mycotic aneurysms.
  • Angiography helps identify aneurysms requiring further intervention due to lack of response or enlargement.

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