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MR findings in kernicterus

V Martich-Kriss1, S S Kollias, W S Ball

  • 1Department of Radiology, Children's Hospital Medical Center, Cincinnati, OH 45229-3039, USA.

AJNR. American Journal of Neuroradiology
|April 1, 1995
PubMed
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Kernicterus, or bilirubin encephalopathy, is visualized on MRI. T2-weighted images reveal high signal intensity in the globus pallidus, indicating bilirubin deposition in the brain.

Area of Science:

  • Neurology
  • Radiology
  • Pediatric Medicine

Background:

  • Kernicterus, a severe form of neonatal hyperbilirubinemia, can lead to permanent neurological damage.
  • Understanding the neuroimaging features of kernicterus is crucial for early diagnosis and intervention.

Observation:

  • This study details the magnetic resonance (MR) imaging characteristics of kernicterus.
  • Specific attention is given to T2-weighted sequences.

Findings:

  • T2-weighted MR images demonstrate bilateral high signal intensity within the globus pallidus.
  • This finding correlates with the known pattern of bilirubin deposition in the brain.

Implications:

  • The MR findings provide a characteristic imaging biomarker for kernicterus.

Related Experiment Videos

  • Accurate identification of these imaging features can aid in diagnosing bilirubin encephalopathy.