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Thrombosis in giant basilar tip aneurysms during coil embolization
1Department of Neuroradiology, Radcliffe Infirmary, Oxford, England.
AJNR. American Journal of Neuroradiology
|April 1, 1995
Summary
Coil embolization of giant basilar tip aneurysms can lead to spontaneous intraaneurysmal thrombosis. This occurs outside the coil mass, likely due to altered blood flow patterns within the aneurysm.
Area of Science:
- Interventional Neuroradiology
- Vascular Neurology
- Neurosurgery
Background:
- Giant basilar tip aneurysms pose significant treatment challenges due to their location and size.
- Coil embolization is a primary endovascular treatment for intracranial aneurysms.
- Understanding aneurysm thrombosis mechanisms is crucial for optimizing treatment outcomes.
Observation:
- Two patients with giant basilar tip aneurysms were treated with coil embolization.
- One patient received both platinum fiber and Guglielmi detachable coils.
- The other patient received Guglielmi detachable coils exclusively.
Findings:
- Spontaneous intraaneurysmal thrombosis occurred in both patients.
- Thrombosis developed outside the coil mass in both cases.
- Altered intraaneurysmal flow dynamics are the presumed cause of thrombosis.
Implications:
- This finding suggests that coil embolization can induce thrombosis in giant aneurysms.
- Disruption of intraaneurysmal flow may be a key factor in promoting thrombosis.
- Further research is warranted to explore this phenomenon and its clinical significance.