Related Experiment Videos
Meningiomas with conspicuous plasma cell-lymphocytic components: a report of five cases
Cancer
|January 1, 1979
Abstract:
Five meningeal neoplasms grossly resembling meningiomas but histologically containing meningothelial cells together with abundant plasma cells and lymphocytes are reported. These masses are regarded as meningiomas with extensive plasma cell--lymphocytic infiltrates.
Insights
This study describes rare meningiomas with significant plasma cell and lymphocyte infiltrates. These tumors exhibit features of both meningiomas and inflammatory conditions.
Area of Science:
- Neuropathology
- Oncology
Background:
- Meningiomas are typically benign tumors arising from the meninges.
- Distinguishing meningiomas from other central nervous system neoplasms is crucial for accurate diagnosis and treatment.
Observation:
- Five cases of meningeal neoplasms with gross resemblance to meningiomas were identified.
- Histological examination revealed meningothelial cells alongside abundant plasma cells and lymphocytes.
Findings:
- The reported meningeal neoplasms are characterized by extensive plasma cell and lymphocytic infiltrates.
- These findings suggest a variant of meningioma with a prominent inflammatory component.
Implications:
- Recognition of this variant is important for accurate neuropathological diagnosis.
- Understanding the inflammatory component may offer insights into tumor microenvironment and potential therapeutic strategies.