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[Protein-energy malnutrition: its effects on 4 metabolic parameters]
E Camarero González1, V Muñoz Leira, M Iglesias Guerrero
1Sección de Nutrición y Dietética (Servicio de Endocrinología y Nutrición), Complejo Hospital Xeral de Galicia, Santiago de Compostela, España.
Nutricion Hospitalaria
|May 1, 1995
Summary
Serum cholinesterase (CS) and cholesterol (CO) show promise in assessing energy-protein malnutrition (EPM). CS, in particular, is a useful indicator for hospitalized patients
Area of Science:
- Clinical Nutrition
- Biochemistry
- Medical Diagnostics
Background:
- Energy-protein malnutrition (EPM) assessment relies on various biomarkers.
- Classic parameters include albumin (ALB) and transferrin (TF).
- Novel markers like cholinesterase (CS) and cholesterol (CO) require further evaluation.
Purpose of the Study:
- To assess the utility of cholinesterase (CS) and cholesterol (CO) in evaluating nutritional status.
- To compare CS and CO with traditional markers albumin (ALB) and transferrin (TF).
- To investigate these markers in patients with energy-protein malnutrition (EPM).
Main Methods:
- Study included 73 patients (17-93 years) with EPM.
- Patients categorized into visceral (V) and non-visceral (NV) EPM groups.
- Evaluated ALB, TF, total lymphocytes (TL), cellular immunity test (CIT), triceps skin fold (TSF), and muscular circumference (MC).
Main Results:
- Significant differences observed between V and NV groups for ALB, TF, TL, and CIT, with lower values in the V group.
- Positive correlations found between TF and ALB, TF and CO, TF and CS, CS and ALB, and CS and CO.
- No significant correlation between ALB and CO.
Conclusions:
- Serum cholinesterase (CS) is a valuable parameter for assessing the nutritional status of hospitalized patients.
- CS and CO demonstrate potential as reliable indicators of EPM.
- Further research can explore the combined use of these markers for comprehensive nutritional assessment.