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Updated: Aug 11, 2026

Optimized Analysis of In Vivo and In Vitro Hepatic Steatosis
Published on: March 11, 2017
[Hyperglycemia in toxic oil syndrome]
A Sáenz Calvo1, M García del Valle, E Cordón Rodríguez
1Centro de Salud Gómez Acebo. Insalud Area/Sector 11 de Madrid.
Objective:
To know the prevalence of hyperglycemia in patients with Spanish toxic oil syndrome (TOS). To analyze clinical, biochemical, and pathological associated factors. To compare them with a control group.
Design:
Case and controls study.
Setting:
Primary Health Care. XI Sanitary district in Madrid.
Patients And Other Participants:
734 cases with toxic oil syndrome. 1474 control subjects.
Measurements And Main Results:
Prevalence of impaired glucose tolerance was 2.95% in TOS and 0.07% in control subjects (p < 0.001; OR, 7.55; IC, 291-19.57). Diabetes No insulin treated was 7.78% in TOS and 3.26% in controls (p < 0.001; OR 250; IC 1.62-3.87). Diabetes insulin treated was 1.99% in TOS and 0.47% in controls (p < 0.01; OR, 4.98; IC, 1.80-13.78). Prevalence of diabetes mellitus in TOS was 9.77 and 3.67% (p < 0.001; OR, 2.85; IC, 1.90-4.25) in controls. The pancreatic lesions found in the necropsies were vasculitis type TOS (4 cases) and endothelial vascular lesions (1 case).
Conclusions:
The prevalence of hyperglycemia in TOS reached 13%, where as in the control subjects, it was 3.8% (p < 0.001). The pancreatic lesions detected in deceased TOS patients did not coincide with those commonly described in diabetes mellitus.
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