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Related Experiment Videos

A feasibility study for removing tissue contamination from porous implants

J M Carr1, D B Levine, A P Bennett

  • 1Dana Center of the Hospital for Special Surgery, New York, NY 10021, USA.

Biomedical Instrumentation & Technology
|May 1, 1995
PubMed
Summary

Discarded porous implants can be decontaminated and resterilized. A novel cleaning method using detergent, nitric acid, and sodium hypochlorite effectively removed tissue contamination, reducing surgical waste.

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Area of Science:

  • Biomaterials science
  • Surgical innovation
  • Medical device reprocessing

Background:

  • Porous implants unpackaged but not used in surgery are discarded due to potential tissue contamination.
  • This leads to significant waste in healthcare settings.
  • Reprocessing these implants could reduce costs and environmental impact.

Purpose of the Study:

  • To develop and validate a decontamination method for porous implants.
  • To enable resterilization and reimplantation of previously discarded devices.
  • To minimize waste associated with surgical implant handling.

Main Methods:

  • A multi-step decontamination process involving ultrasonic scrubbing.
  • Sequential immersion in aqueous solutions: dishwashing detergent, 7% nitric acid, and 5.25% sodium hypochlorite.

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  • Validation using protein assays, immune cell activation assays, bioburden testing, and weight comparison.

    • Main Results:

    • No detectable tissue remnants were found on decontaminated porous implant samples.
    • Weight comparisons confirmed no significant material loss.
    • Protein removal assays and immune cell activation tests showed complete decontamination.
    • Bioburden evaluations indicated effective sterilization.

    Conclusions:

    • The developed decontamination method is effective in removing tissue contamination from porous implants.
    • This process allows for the safe resterilization and potential reimplantation of previously discarded devices.
    • The method offers a viable solution to reduce waste in surgical settings.