Related Experiment Video
Updated: Aug 11, 2026

12:18
Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
Boarding school outbreak of group A streptococcal pharyngitis
A A Rushdy1, R P Cooke, A M Iversen
1East Sussex Health Authority.
Communicable Disease Report. CDR Review
|June 23, 1995
Summary
A Streptococcus pyogenes outbreak in a boarding school was linked to poor ventilation in specific dormitories. Prompt treatment of all identified cases and carriers effectively controlled the pharyngitis outbreak.
Area of Science:
- Epidemiology
- Infectious Disease Control
- Public Health
Background:
- Group A beta-haemolytic Streptococcus pyogenes (S. pyogenes) is a common cause of pharyngitis.
- Outbreaks in close-living settings like boarding schools necessitate rapid identification and control measures.
Purpose of the Study:
- To investigate an outbreak of S. pyogenes pharyngitis in a boarding school.
- To identify transmission factors and implement control strategies.
Main Methods:
- Conducted a point-prevalence survey involving throat swabbing of all pupils and staff.
- Epidemiological analysis to determine attack rates and identify high-risk areas.
- Clinical assessment of symptomatic individuals.
Main Results:
- Identified 14 S. pyogenes pharyngitis cases and 16 asymptomatic carriers among pupils, plus one staff case.
- Significantly higher attack rates were observed in two specific dormitories compared to others.
- Poor ventilation was noted in the dormitories with the highest case numbers.
Conclusions:
- The S. pyogenes outbreak was effectively controlled by treating all identified cases and carriers.
- Environmental factors, particularly poor ventilation in dormitories, likely contributed to airborne transmission and higher attack rates in affected areas.
Related Concept Videos
Acute Pharyngitis
Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Tonsillitis I: Introduction
Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
Etiology
Three primary contributing factors have been identified.
Rheumatic Heart Disease I: Introduction
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
Streptococcal Pharyngitis
Streptococcal pharyngitis, commonly known as “strep throat,” is an acute infection of the oropharyngeal tissues caused by the Gram‑positive Group A Streptococcus (Streptococcus pyogenes). Transmission occurs primarily through respiratory droplets expelled during coughing, sneezing, or talking.Mechanisms of Host Entry and Immune EvasionUpon entering the host, S. pyogenes adheres to the mucosal epithelial cells of the pharynx via surface proteins, notably lipoteichoic acid and the antiphagocytic...
Diphtheria
Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...
Bacterial Gastroenteritis
Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...

