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The expression of ferritin on renal cancers and its relationship with cellular differentiation and tumour stage
1Department of Surgery, Tri-Service General Hospital, Taipei, Taiwan, Republic of China.
Objectives:
To investigate ferritin expression in renal carcinoma and the correlation of expression with tumour differentiation and stage.
Patients And Methods:
Ferritin was immunohistologically detected in 35 patients (23 men and 12 women; mean age 58.2 years, range 40-82) with renal carcinoma and the findings compared with cellular type, tumour stage and the ferritin expression of a similar control population of 16 patients.
Results:
The incidence of ferritin expression in renal carcinomas was 51%. Expression was significantly related to tumour stage and not cellular type.
Conclusion:
The results of this study re-emphasize the high expression of ferritin in renal cell carcinoma and the correlation of expression with tumour behaviour.
