Progressive hemifacial atrophy (Parry-Romberg syndrome). Case report

Area of Science:

• Neurology
• Dermatology
• Genetics

Background:

• Progressive hemifacial atrophy, also known as Parry-Romberg syndrome, is a rare disorder characterized by gradual wasting of facial tissues.
• The condition typically involves subcutaneous fat, skin, cartilage, and bone on one side of the face.
• It progresses over a period of 2 to 10 years, eventually reaching a stable phase.

Observation:

• This article reviews existing literature on Parry-Romberg syndrome.
• A specific case report details unique dental manifestations associated with the syndrome.
• The case highlights the complex and varied presentation of facial atrophy.

Findings:

• Parry-Romberg syndrome involves progressive, unilateral facial tissue atrophy.
• Dental anomalies can be a significant, though often overlooked, consequence of the disease process.
• The review synthesizes current knowledge and presents novel clinical observations.

Implications:

• Understanding the full spectrum of Parry-Romberg syndrome, including dental involvement, is crucial for comprehensive patient care.
• Early recognition and management can potentially mitigate long-term functional and aesthetic deficits.
• Further research into the etiology and treatment of Parry-Romberg syndrome is warranted.