Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Aortic-cardiac reflex during dynamic exercise

X Shi1, J T Potts, P B Raven

  • 1Department of Physiology, University of North Texas Health Science Center, Fort Worth 76107, USA.

Journal of Applied Physiology (Bethesda, Md. : 1985)
|April 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2016
Same author

New Agent in the Treatment of Cystinuria: N-acetyl-D-penicillamine.

British medical journal·2010
Same author

Dynamic blood pressure control and middle cerebral artery mean blood velocity variability at rest and during exercise in humans.

Acta physiologica (Oxford, England)·2007
Same author

Targeted deletion of neurokinin-1 receptor expressing nucleus tractus solitarii neurons precludes somatosensory depression of arterial baroreceptor-heart rate reflex.

Neuroscience·2007
Same author

Discharge patterns of somatosensitive neurons in the nucleus tractus solitarius of the cat.

Neuroscience·2005
Same author

Standing up to the challenge of standing: a siphon does not support cerebral blood flow in humans.

American journal of physiology. Regulatory, integrative and comparative physiology·2004
Same journal

Thoroughbred horses susceptible to Recurrent Exertional Rhabdomyolysis have elevated skeletal muscle mitochondrial capacities.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same journal

Change in Neutrophil-to-Lymphocyte Ratio after acute and chronic exercise: A Systematic Review and Meta-Analysis.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same journal

Ankylosing spondylitis and muscle sympathetic nerve activity: a case study.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same journal

Intracranial vasomotor and blood flow responses to light intensity aerobic exercise in young adults: a 4D flow MRI study.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same journal

Comparative assessments of the COSMED adaptive mixing chamber vs. breath-by-breath methods for oxygen uptake measurements in recreationally active adults.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same journal

Can we assess exercise metabolism from skin? Metabolomic profiles in skin dialysate collected during exercise.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
See all related articles

Low-intensity cycling did not alter the aortic-cardiac reflex gain during phenylephrine infusion in healthy volunteers. This suggests exercise does not significantly impact baroreflex sensitivity under these specific conditions.

Area of Science:

  • Cardiovascular Physiology
  • Exercise Physiology
  • Autonomic Nervous System Function

Background:

  • The aortic-cardiac reflex is crucial for regulating heart rate and blood pressure.
  • Understanding how exercise affects this reflex is important for cardiovascular health.
  • Previous research has yielded mixed results on exercise's impact on baroreflex sensitivity.

Purpose of the Study:

  • To investigate the aortic-cardiac reflex gain during low-intensity cycling in healthy individuals.
  • To assess the baroreflex function using the ratio of change in heart rate to mean arterial pressure (delta HR/delta MAP).

Main Methods:

  • 10 healthy volunteers participated in the study.
  • Baroreflex function was assessed using phenylephrine (PE) infusion to induce controlled blood pressure increases.

Related Experiment Videos

  • The aortic-cardiac reflex gain was calculated using PE combined with lower body negative pressure (LBNP) and neck pressure (NP).
  • Exercise involved cycling at approximately 25% maximal O2 uptake.

    • Main Results:

    • Low-intensity cycling significantly increased heart rate, mean arterial pressure, cardiac output, and oxygen uptake.
    • Despite physiological changes during exercise, the change in mean arterial pressure, change in heart rate, and the delta HR/delta MAP ratio were not statistically different between rest and exercise during PE infusion.
    • Phenylephrine infusion increased central venous pressure, which returned to baseline with LBNP application during both rest and exercise.

    Conclusions:

    • Low-intensity cycling does not significantly alter the aortic-cardiac reflex gain in healthy individuals.
    • Baroreflex sensitivity, as assessed by delta HR/delta MAP during PE infusion, remains unchanged during mild exercise.
    • These findings contribute to understanding cardiovascular autonomic regulation during physical activity.