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Axillary granular parakeratosis
D A Mehregan1, P Vandersteen, L Sikorski
1Pinkus Dermatopathology Laboratory, P.C., Monroe, Michigan 48161, USA.
Journal of the American Academy of Dermatology
|August 1, 1995
Summary
Axillary granular parakeratosis is a rare skin condition causing itchy, dark patches in the armpit. It is likely a reaction to antiperspirants or deodorants.
Area of Science:
- Dermatology
- Histopathology
Background:
- Axillary granular parakeratosis is a distinct skin condition.
- Its etiology is currently unknown.
Observation:
- Two patients presented with mildly itchy, hyperpigmented axillary patches.
- Histopathology revealed thickened stratum corneum with compact parakeratosis and retained keratohyalin granules.
Findings:
- The stratum corneum measured 90-185 microns in thickness.
- Distinctive histopathologic features include compact parakeratosis and preserved stratum granulosum.
Implications:
- This condition may represent a contact reaction to antiperspirants or deodorants.
- Further research is needed to confirm the etiology and guide treatment.