Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Parathyroid hormone and the cellular immune system

R Shurtz-Swirski1, T Shkolnik, S M Shasha

  • 1Renal Unit, Western Galilee Hospital, Nahariya, Israel.

Nephron
|January 1, 1995
PubMed
Summary

Parathyroid hormone (PTH) influences immune cell function, potentially impairing immune responses in chronic renal failure (CRF) patients. This review explores PTH

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Changes of trends in the size of the dental implants in recent years Part 1. The role of short implants in dental implantology The literature review.

Fogorvosi szemle·2018
Same author

Calcium channel blocker effect on insulin resistance and inflammatory markers in essential hypertension patients.

International angiology : a journal of the International Union of Angiology·2013
Same author

[10th Nahariya meeting on morbidity and medicine in the Holocaust].

Harefuah·2011
Same author

Primed polymorphonuclear leukocytes constitute a possible link between inflammation and oxidative stress in hyperlipidemic patients: effect of statins.

Minerva cardioangiologica·2010
Same author

The combined effect of calcium channel blocker Lercanidipine and antioxidants on low-grade systemic inflammation parameters in essential hypertension patients.

Minerva cardioangiologica·2008
Same author

Oxidative stress and inflammation due to peripheral polymorphonuclear leukocytes after coronary angiography vs percutaneous coronary intervention.

Minerva cardioangiologica·2008

Area of Science:

  • Endocrinology
  • Immunology
  • Nephrology

Background:

  • Parathyroid hormone (PTH) is crucial for calcium homeostasis.
  • Emerging evidence suggests PTH possesses immunomodulatory roles.
  • Chronic renal failure (CRF) is associated with elevated PTH levels.

Purpose of the Study:

  • To review the impact of PTH on diverse immune functions.
  • To explore the implications of PTH in CRF.

Main Methods:

  • Literature review of studies investigating PTH and immune responses.
  • Analysis of data on immune cell function in CRF patients with hyperparathyroidism.

Main Results:

  • Elevated PTH in CRF correlates with impaired polymorphonuclear leukocyte migration, phagocytosis, and bactericidal activity.
  • PTH affects antibody production and T and B lymphocyte proliferation in vitro and in vivo.
  • PTH fragments may play a role in CRF pathogenesis.

Conclusions:

  • PTH exhibits significant immunomodulatory effects.
  • Dysregulation of PTH in CRF can compromise immune competence.
  • Further research into PTH's immune role is warranted for CRF management.

Related Experiment Videos