Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Calcium binding by dietary fibre

W P James, W J Branch, D A Southgate

    Lancet (London, England)
    |March 25, 1978
    PubMed
    Summary

    Dietary fiber binds calcium, reducing its absorption in the small intestine. However, colon microbes release this calcium, suggesting the colon

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The global epidemic of obesity.

    Asia Pacific journal of clinical nutrition·2014
    Same author

    Obesity: translating scientific research into therapeutic and preventive benefit.

    The International journal of risk & safety in medicine·2013
    Same author

    Achieving weight-loss maintenance.

    Postgraduate medicine·2009
    Same author

    Oxidants, antioxidants and cardiovascular disease.

    Nutrition research reviews·2008
    Same author

    Food and health in Europe: a new basis for action.

    WHO regional publications. European series·2004
    Same author

    The role of sibutramine in weight management--towards a blueprint for a sibutramine weight management system.

    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity·2002

    Area of Science:

    • Nutritional Science
    • Gastroenterology
    • Plant Biochemistry

    Background:

    • Dietary fiber intake is crucial for health.
    • Phytate in plants can inhibit mineral absorption.
    • Calcium balance is vital for bone health and overall physiology.

    Purpose of the Study:

    • To investigate the interaction between dietary fiber, phytate, and calcium bioavailability.
    • To elucidate the role of uronic acids in fiber-calcium binding.
    • To understand the colonic adaptation for calcium absorption in high-fiber diets.

    Main Methods:

    • Analysis of calcium binding by plant fiber fractions.
    • Quantification of uronic acid content in fiber.
    • Assessment of calcium absorption in the small intestine and colon.

    Main Results:

    • Plant fiber, particularly its non-cellulosic fraction rich in uronic acids, binds significant amounts of calcium.
    • This binding reduces calcium availability for absorption in the small intestine.
    • Colonic microbial digestion of uronic acids liberates bound calcium, enabling colonic absorption.

    Conclusions:

    • The availability of calcium from high-fiber diets depends on the interplay between small intestinal binding and colonic microbial processing.
    • The colon's adaptive capacity for calcium absorption is a key factor in maintaining calcium balance on high-fiber diets.
    • Uronic acid content in dietary fiber influences calcium bioavailability through differential absorption in the small intestine and colon.

    Related Experiment Videos