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Updated: Sep 21, 2026

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 17, 2014
Incidence of congenital heart disease: I. Postnatal incidence
1Department of Pediatrics, University of California-San Francisco 94143, USA.
Insights
Congenital heart disease (CHD) incidence remains stable in industrialized nations, with advanced diagnostics improving detection of even minor heart defects. Global CHD lesion distribution is similar, though some conditions are less common in developing countries.
Area of Science:
- Cardiology
- Pediatrics
- Public Health
Background:
- Congenital heart disease (CHD) incidence in Western countries shows wide variation.
- Improved diagnostic tools like echocardiography have enhanced detection capabilities.
- Historical data may be skewed by diagnostic limitations and surgical advancements.
Purpose of the Study:
- To analyze trends in congenital heart disease incidence.
- To compare CHD lesion distribution globally.
- To assess the impact of diagnostic advancements on reported incidence rates.
Main Methods:
- Review of historical and contemporary epidemiological data on CHD.
- Analysis of diagnostic capabilities over time, including echocardiography with Doppler color flow.
- Comparison of CHD prevalence and lesion types between industrialized and developing nations.
Main Results:
- No significant increase in CHD incidence observed over the past 20-30 years, despite improved diagnostics.
- Echocardiography enables detection of previously undiagnosed asymptomatic or minor CHD.
- CHD lesion distribution is broadly similar worldwide, with noted exceptions like aortic stenosis and coarctation of the aorta in developing countries.
Conclusions:
- Current diagnostic advancements have refined CHD detection without altering underlying incidence.
- Global surveillance of CHD is crucial, though data from underdeveloped countries remain limited.
- Understanding lesion distribution aids in targeted healthcare resource allocation for congenital heart disease.
Abstract:
The incidence of congenital heart disease (CHD) in the Western industrialized world has varied from a low value of about 3 to 5 per 1000 live births to about 12 per 1000 live births. Most of the lower incidence figures were obtained before there were sufficiently well trained pediatric cardiologists and before the success of cardiac surgery put a premium on early and correct diagnosis of CHD. The advent of echocardiography with Doppler color flow measurements has made it possible to diagnose lesions that are asymptomatic, minor, and even without murmurs. Given these differences, there does not appear to have been a significant increase in the incidence of CHD over the last 20-30 years. The incidence of CHD in underdeveloped countries is not known, but the distribution of different lesions is fairly similar to those in developed countries except perhaps for fewer with aortic stenosis and coarctation of the aorta.
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