The rat-pull test procedure: a method for assessing the strength of rats

A novel method for the measurement of rat strength is described. The method makes use of a rat's natural inclination to move forcibly and rapidly toward an enclosed, darkened compartment. Acrylamide (200.0 mg/kg, IP), gentamicin (30.0 mg/kg, IP), d-tubocurarine (0.1 mg/kg, IP), and diazepam (3.0, 10.0, and 30.0 mg/kg, PO) significantly decreased strength. The rat-pull test procedure provides a sensitive, reliable, and valid method for the measurement of strength in rats.