[Radiotherapy of hypophyseal adenoma]

The efficacy of radiotherapy alone for control of pituitary adenoma is well documented. Because of slow endocrinologic response and delayed shrinkage of the tumor, it is reserved for inoperable patients. Transsphenoidal surgery is generally regarded as the treatment of choice. It provides prompt reduction of tumor mass and hormone levels. Radiotherapy as an adjunct has been proven effective in gross residual disease and for post-operatively elevated hormone levels. It is also effective in treating recurrencies after surgery. Its value in an interdisciplinary approach is discussed.