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Related Experiment Videos

Vitamins as therapy in the 1990s

R Swain1, B Kaplan

  • 1Department of Family Medicine and Sports Medicine, West Virginia University, Charleston 25301, USA.

The Journal of the American Board of Family Practice
|May 1, 1995
PubMed
Summary

Vitamins are now recognized for therapeutic uses beyond preventing deficiency. This review highlights vitamin A, D, niacin, folate, and antioxidants for treating various conditions and preventing diseases.

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Area of Science:

  • Nutritional Science
  • Dermatology
  • Endocrinology
  • Preventive Medicine

Background:

  • Vitamins were historically viewed solely as essential nutrients for preventing deficiency syndromes.
  • Current medical practice increasingly utilizes vitamins and their derivatives as therapeutic agents.

Purpose of the Study:

  • To review the therapeutic applications of vitamins in medicine.
  • To provide recommendations for vitamin use in treatment and prevention based on current literature.

Main Methods:

  • Conducted a MEDLINE literature search for clinical reviews and original studies (1990-1994).
  • Included cross-referencing from bibliographies of retrieved papers and pre-1990 research.
  • Focused on the use of vitamins and their derivatives in medical treatments.

Main Results:

  • Topical vitamin A derivatives (tretinoin) are effective for acne and skin aging.
  • Oral vitamin A derivatives (isotretinoin, etretinate) treat severe acne and psoriasis.
  • Vitamin D3 aids osteoporosis prevention in postmenopausal women; topical vitamin D benefits psoriasis.
  • Niacin reduces serum cholesterol; folate prevents neural tube defects preconceptionally.
  • Antioxidants (vitamins C, E, beta-carotene) show potential in preventing atherosclerosis and cancer.

Conclusions:

  • Vitamins have established therapeutic roles in dermatology, endocrinology, and preventive medicine.
  • Specific vitamin derivatives offer targeted treatments for conditions like acne, psoriasis, and osteoporosis.
  • Folate supplementation and antioxidant use hold promise for pregnancy health and chronic disease prevention.

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