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Related Experiment Videos

Antifungal agents: an overview. Part II

A K Gupta1, D N Sauder, N H Shear

  • 1Department of Medicine, Sunnybrook Health Science Centre, Toronto, Ontario, Canada.

Journal of the American Academy of Dermatology
|June 1, 1994
PubMed
Summary

New antifungal drugs, including azoles, allylamines, and amorolfine, are set to significantly change the treatment of fungal infections like onychomycosis.

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Area of Science:

  • Mycology
  • Pharmacology
  • Dermatology

Background:

  • Fungal infections (mycoses) require effective therapeutic options.
  • Onychomycosis, a common superficial mycosis, presents treatment challenges.

Purpose of the Study:

  • To review a new generation of antifungal drugs.
  • To discuss their potential impact on treating mycoses, especially onychomycosis.

Main Methods:

  • In-depth literature review of antifungal agents.
  • Focus on azoles, allylamines, and morpholine derivatives.

Main Results:

  • New antifungal drugs offer promising therapeutic alterations.
  • Azoles (itraconazole, fluconazole), allylamines (naftifine, terbinafine), and amorolfine are key agents.

Conclusions:

  • The reviewed antifungal agents are expected to significantly impact mycoses therapy.
  • These drugs represent advancements in managing systemic and superficial fungal infections.

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