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[Hypokalemic rhabdomyolysis and thiazide diuretics. 3 clinical cases]
S S Girola1, A Mazzone, M Moroni
1Istituto di Terapia Medica, Università degli Studi, IRCCS Policlinico San Matteo di Pavia.
Annali Italiani Di Medicina Interna : Organo Ufficiale Della Societa Italiana Di Medicina Interna
|April 1, 1995
Abstract:
Rhabdomyolysis is an acute skeletal muscle disorder characterized by altered integrity of the cell membranes of muscle fiber cells and can be caused by a variety of factors whose nature is not necessarily traumatic. Hypokalemia is one of the most common metabolic causes, accounting for about 14-28% of rhabdomyolytic syndromes. We report and discuss three cases of hypokalemia caused by diuretic treatment with hydrochlorothiazide: the main clinical features were muscle symptoms following massive rhabdomyolysis.