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Percutaneous serial catheterization in swine: a practical approach

C H Gaymes1, M M Swindle, P C Gillette

  • 1Medical University of South Carolina, Charleston, USA.

Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research
|March 1, 1995
PubMed
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Correction.

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Percutaneous femoral cardiac catheterization is a practical technique for swine cardiovascular studies. This method is especially useful for studies needing multiple, serial catheterizations, proving its feasibility in animal models.

Area of Science:

  • Veterinary Medicine
  • Cardiovascular Research
  • Surgical Techniques

Background:

  • Experimental cryoablation of the His bundle requires repeated cardiac catheterizations in swine models.
  • Establishing reliable vascular access is crucial for the success of these serial procedures.

Purpose of the Study:

  • To evaluate the feasibility and practicality of percutaneous femoral cardiac catheterization in swine for cardiovascular studies.
  • To assess the efficacy of this technique in models requiring multiple and follow-up catheterizations.

Main Methods:

  • Femoral percutaneous cannulations were attempted in 15 swine (Yucatan, Hanford, Yorkshire) weighing 15-50 kg.
  • Follow-up catheterizations were performed, with a cutdown approach used for failed percutaneous attempts.

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Main Results:

  • Percutaneous femoral cannulation was successful in 14 of 15 swine across different breeds.
  • In follow-up procedures, percutaneous access succeeded in 6 of 10 animals, while cutdown was successful in the remaining 4.

Conclusions:

  • Percutaneous femoral cardiac catheterization is a feasible and practical method for swine cardiovascular research.
  • This technique is particularly advantageous for studies necessitating multiple and serial catheterizations, enhancing experimental design.