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Procedural memory and Parkinson's disease

H Allain1, A Lieury, V Quemener

  • 1Laboratoire de Pharmacologie, Faculté de Médecine, Université de Haute-Bretagne, Rennes, France.

Dementia (Basel, Switzerland)
|May 1, 1995
PubMed
Summary
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Parkinson's disease (PD) significantly impairs both declarative and procedural memory. Research indicates these memory deficits are linked to age and the disease's progression, affecting automatism.

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Neurology

Background:

  • Parkinson's disease (PD) is associated with cognitive disorders.
  • Understanding mnestic deficits in PD is crucial for explaining associated cognitive impairments.

Purpose of the Study:

  • To investigate the extent of declarative and procedural memory impairment in Parkinson's disease.
  • To compare memory functioning in PD patients with healthy control groups.

Main Methods:

  • A group of 16 Parkinson's disease patients with controlled motor function participated.
  • Memory was assessed using three tests: inverted reading, braille reading, and sound form association.
  • Performance was compared against young and aged healthy control groups.

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Main Results:

  • Parkinson's disease patients exhibited significant deficits in both declarative and procedural memory.
  • Declarative memory impairment in PD was more pronounced than in age-matched healthy controls.
  • Procedural memory deficits were correlated with patient age and disease severity, suggesting a loss of automatism.

Conclusions:

  • Parkinson's disease leads to substantial impairments in both declarative and procedural memory.
  • The findings suggest that procedural memory deficits in PD may relate to a loss of automaticity.
  • Further research into akinesia and motor disorders should consider the role of automatic memory impairment.