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Colonic medication bezoar from extended-release nifedipine and procainamide
1Department of Medicine, Veterans Affairs Medical Center, Minneapolis, USA.
Archives of Family Medicine
|August 1, 1995
Summary
A rare colonic bezoar formed from extended-release nifedipine and procainamide was observed. Increased use of extended-release medications may lead to more bezoar cases in susceptible individuals.
Area of Science:
- Gastroenterology
- Pharmacology
Background:
- Bezoars are rare gastrointestinal concretions.
- Extended-release (ER) drug formulations are increasingly common.
Observation:
- A case of a primary colonic bezoar composed of ER nifedipine and ER procainamide is presented.
- The bezoar formed within the colon.
Findings:
- This case highlights an unusual etiology for bezoar formation.
- Extended-release formulations of commonly prescribed medications can aggregate.
Implications:
- The incidence of ER medication bezoars may rise in vulnerable populations.
- Clinicians should consider bezoars in patients with refractory constipation on ER medications.
- Awareness and suspicion are crucial for timely diagnosis and management.