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Non-destructive analysis of the protein conformational structure of human pituitary adenomas using reflectance FT-IR
1Neurological Institute, Veterans General Hospital-Taipei, Taiwan, Republic of China.
Cancer Letters
|July 20, 1995
Abstract:
Reflectance Fourier-transform infrared microspectroscopy was used to determine the secondary structure and composition of the different human pituitary adenomas. Non-functioning pituitary adenomas exhibited similar protein secondary structure and conformational composition, but active pituitary adenomas revealed different behavior. The differences in secondary structure for the different human pituitary adenomas might possibly be due to the different protein conformations of the proliferated adenoma tissues and various hormones shared.