Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Surgery from a US perspective

J B Dekernion1, J R Franklin, A Belldegrun

  • 1Department of Surgery, UCLA School of Medicine, USA.

Cancer Surveys
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

T-cell recruitment: a tool for specific immunosuppression.

Immunology today·2014
Same author

Immunotherapy and gene therapy for genitourinary malignancies.

International journal of urology : official journal of the Japanese Urological Association·2013
Same author

Chemotherapy of experimental transitional-cell carcinoma.

Urology·2011
Same author

Interferon Alpha, GM-CSF-Activated T Cells, and IL-6 in Renal Cell Carcinoma.

Methods in molecular medicine·2011
Same author

Joint association of polymorphism of the FGFR4 gene and mutation TP53 gene with bladder cancer prognosis.

British journal of cancer·2006
Same author

Therapeutic strategies, predicting outcomes in patients with renal cell and transitional cell carcinomas.

Reviews in urology·2006

Radical prostatectomy can cure organ-confined prostate cancer in men with a long life expectancy. Early detection using prostate-specific antigen (PSA) improves outcomes and disease-free survival rates.

Area of Science:

  • Urology
  • Oncology
  • Surgical Oncology

Background:

  • Prostate screening enables early detection of organ-confined prostate carcinoma.
  • Radical prostatectomy is a treatment option for localized prostate cancer, aiming to minimize morbidity and mortality.

Purpose of the Study:

  • To evaluate the efficacy and outcomes of radical prostatectomy for organ-confined prostate cancer.
  • To assess the impact of prostate-specific antigen (PSA) monitoring on disease-free survival.

Main Methods:

  • Retrospective analysis of patients with clinically localized prostate cancer treated with radical retropubic prostatectomy and lymph node dissection.
  • Monitoring of disease progression using prostate-specific antigen (PSA) concentrations.

Main Results:

Related Experiment Videos

  • 5 and 10-year crude survival rates were 96% and 86% respectively.
  • Tumor penetration of the prostatic capsule and seminal vesicle involvement significantly compromised survival.
  • Patients diagnosed and treated more recently showed improved disease-free survival due to earlier PSA detection.
  • 92% of patients with pathologically organ-confined tumors were disease-free with undetectable PSA at 5 years.

Conclusions:

  • Radical prostatectomy can effectively cure organ-confined prostate cancer with acceptable morbidity.
  • Early detection and treatment, particularly in younger patients, significantly benefit from radical prostatectomy for prostate cancer eradication.