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Updated: Oct 23, 2026

Integrated Compensatory Responses in a Human Model of Hemorrhage
Published on: November 20, 2016
[The characteristics of individual reactions of the central hemodynamics to trauma]
Abstract:
Experiments with white mongrel male rats subjected to the standard trauma according to Kennon have revealed four types of responses of the central haemodynamics. The minimal mortality rate (31-38% for the first three days) was registered for hyper- and eudynamic types when the heart productivity parameters and atmospheric pressure either exceeded or were almost similar to those of intact animals. A decrease of these parameters (a hypodynamic type) has led to increase of the mortality rate (to 58%), but a sharp (more then 3 times) decrease of the cardiac index was characterized by a progressive increase of the arterial pressure and maximal mortality rate.
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