Related Experiment Videos
A novel phorbol ester from Excoecaria agallocha
K L Erickson1, J A Beutler, J H Cardellina
1Laboratory of Drug Discovery Research and Development, National Cancer Institute, NCI-FCRDC, Maryland 21702-1201, USA.
Journal of Natural Products
|May 1, 1995
Abstract:
The novel phorbol ester 12-deoxyphorbol 13-(3E,5E-decadienoate) [1] was isolated as the anti-HIV principle of Excoecaria agallocha leaves and stems collected in northwest Australia. The structure was determined by spectral means. Compound 1 was also a potent displacer of [3H]-phorbol dibutyrate from rat brain membranes.