[High dosage immunoglobulin therapy in Rhesus incompatibility]

From September 1992 to the end of August 1993 we treated fourteen children who suffered from rhesus hemolytic disease with high-dose intravenous immune globulin G. Eleven patients did not require an exchange transfusion, three needed an exchange transfusion despite immune globulin therapy. Although an exchange transfusion cannot be avoided in all patients, this new method is an important addition to the currently available possibilities of treatment. It is without adverse side effects and helps to lower the number of exchange transfusions.