[Nonfamilial cherubism. A clinical case report]

Area of Science:

• Oral and Maxillofacial Surgery
• Genetics
• Radiology

Background:

• Cherubism is a rare genetic disorder characterized by progressive, bilateral, symmetrical fibro-osseous lesions of the jaws.
• While typically familial, non-familial cases present unique diagnostic and management challenges.

Observation:

• A rare case of non-familial cherubism is presented with a six-year clinical follow-up.
• The study analyzes the disease's hereditary transmission patterns, anatomopathological features, and radiological characteristics.
• Differential diagnosis considerations for similar jaw lesions are discussed.

Findings:

• Computed Tomography (CT) is crucial for identifying lesions missed by standard X-rays and orthopantomography.
• Conservative surgical approaches prioritizing the preservation of dental and bone tissue are vital.

Implications:

• This case highlights the importance of advanced imaging in diagnosing rare conditions like cherubism.
• Emphasizes the need for meticulous surgical planning to maximize functional and aesthetic outcomes in managing fibro-osseous jaw lesions.