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Cognitive effects of a new pyrrolidine derivative (levetiracetam) in patients with epilepsy
L G Neyens1, W C Alpherts, A P Aldenkamp
1Epilepsy centre, Heemstede, The Netherlands.
Abstract:
1. A new pyrrolidine derivative (levetiracetam), resembling piracetam, was given as antiepileptic concomitant drug to patients with chronic epilepsy. 2. In a single-blind add-on rising-dose study the cognitive side-effects were investigated twice after one week of administration. 3. The results did not show any significant changes in cognitive performances.