[The role of middle-molecule peptides in the pathogenesis of traumatic disease]

On the basis of study of mass-spectrum of blood plasma ultrafiltrate in 21 injures with severe associated trauma during first four posttraumatic days and in healthy persons one can suggest that combinations with molecular weights of 300-1050 Da are to be one of the important regulatory mechanisms of posttraumatic adaptative processes. With increasing of the injury gravity reorientation of the levels of adaptative reactions management and level enhancing of mediomolecular regulators are found to be occurred.