Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Neurosyphilis and AIDS]

M J Quaresma1, E Valadas, J J Ferreira

  • 1Serviço de Doenças Infecciosas, Hospital de Santa Maria, Lisboa.

Acta Medica Portuguesa
|May 1, 1995
PubMed
Summary

Syphilis progresses rapidly to neurosyphilis in HIV patients, even with early treatment. Diagnosis is complex, requiring high-dose, long-term intravenous penicillin therapy.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Aspirin in diabetic patients at primary prevention: insights of the VITAL cohort.

Journal of endocrinological investigation·2023
Same author

Reply to the letter 'We never speak about sudden unexpected death in Parkinson's disease'.

European journal of neurology·2020
Same author

Contingent negative variation: a biomarker of abnormal attention in functional movement disorders.

European journal of neurology·2020
Same author

Reply to letter: Does Parkinson's disease increase the risk of cardiovascular events? A systematic review and meta-analysis.

European journal of neurology·2019
Same author

Does Parkinson's disease increase the risk of cardiovascular events? A systematic review and meta-analysis.

European journal of neurology·2019
Same author

Long-term efficacy of opicapone in fluctuating Parkinson's disease patients: a pooled analysis of data from two phase 3 clinical trials and their open-label extensions.

European journal of neurology·2019

Area of Science:

  • Infectious Diseases
  • HIV/AIDS Research
  • Neurology

Background:

  • Syphilis presents unique challenges in individuals with Human Immunodeficiency Virus (HIV) infection.
  • Co-infection with HIV can accelerate syphilis progression to advanced stages.

Observation:

  • Neurosyphilis, a severe complication, develops more rapidly in HIV-positive individuals.
  • Standard early-stage syphilis treatment may not prevent rapid progression to neurosyphilis.

Findings:

  • Diagnosing neurosyphilis in HIV patients is complex, with serological tests lacking definitive accuracy.
  • Effective treatment necessitates high-dose, prolonged intravenous penicillin administration.

Implications:

  • Clinical vigilance is crucial for managing syphilis in HIV-infected populations.
  • Treatment protocols for neurosyphilis in HIV patients may require adjustments.
  • Further research into diagnostic and therapeutic strategies is warranted.

Related Experiment Videos