Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

SPECT imaging of stroke

J C Masdeu1, L M Brass

  • 1Department of Neurology, New York Medical College, St. Vincent's Medical Center, NY 10011, USA.

Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging
|July 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

"Ears of the Lynx" MRI Sign Is Associated with SPG11 and SPG15 Hereditary Spastic Paraplegia.

AJNR. American journal of neuroradiology·2019
Same author

Gender difference in prognosis after transient cerebral ischemia or minor stroke.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2015
Same author

Intracranial arteries in individuals with the elastin gene hemideletion of Williams syndrome.

AJNR. American journal of neuroradiology·2013
Same author

Midbrain presynaptic dopamine tone predicts sustained and transient neural response to emotional salience in humans: fMRI, MEG and FDOPA PET.

Molecular psychiatry·2012
Same author

EFNS guidelines on the use of neuroimaging in the management of motor neuron diseases.

European journal of neurology·2010
Same author

Boosting enrollment in neurology trials with Local Identification and Outreach Networks (LIONs).

Neurology·2009
Same journal

Machine Learning for Distal Medium-Vessel Occlusion Detection: Advances, Challenges, and Future Directions.

Journal of neuroimaging : official journal of the American Society of Neuroimaging·2026
Same journal

Impact of Synthetic Lesional MR Images in Automated Focal Cortical Dysplasia Detection in Low-Data Scenarios.

Journal of neuroimaging : official journal of the American Society of Neuroimaging·2026
Same journal

Association of Acute Ischemic Stroke Volume With Post-Stroke Epilepsy Development.

Journal of neuroimaging : official journal of the American Society of Neuroimaging·2026
Same journal

Annual Meeting of the American Society of Neuroimaging Puerto Rico, January 2026.

Journal of neuroimaging : official journal of the American Society of Neuroimaging·2026
Same journal

Proceedings of the 49th Annual Meeting of the American Society of Neuroimaging.

Journal of neuroimaging : official journal of the American Society of Neuroimaging·2026
Same journal

Facial Nerve Tractography of Vestibular Schwannomas: A Systematic Review of MR Acquisition and Analysis Pipelines.

Journal of neuroimaging : official journal of the American Society of Neuroimaging·2026
See all related articles

Single-photon emission computed tomography (SPECT) aids stroke management by accurately imaging brain ischemia and predicting outcomes. This nuclear medicine technique offers advantages over other imaging modalities in acute stroke and vascular assessment.

Area of Science:

  • Neurology
  • Nuclear Medicine
  • Radiology

Background:

  • Single-photon emission computed tomography (SPECT) is a valuable imaging modality in neurological diagnostics.
  • Its application in stroke management requires clear definition and optimization.

Purpose of the Study:

  • To elucidate the multifaceted roles of brain perfusion SPECT in the clinical management of stroke patients.
  • To compare SPECT's accuracy against other neuroimaging techniques in acute stroke.
  • To explore SPECT's utility in prognostication and assessment of cerebrovascular conditions.

Main Methods:

  • Utilized brain perfusion SPECT imaging in various stroke scenarios.
  • Compared SPECT findings with computed tomography (CT) and magnetic resonance imaging (MRI) in acute stroke.

Related Experiment Videos

  • Assessed SPECT's role in evaluating transient ischemic attacks (TIAs), lacunar vs. cortical strokes, and post-thrombolysis reperfusion.
  • Employed acetazolamide challenge SPECT to evaluate cerebrovascular reserve in patients with stenosis.
  • Integrated SPECT with transcranial Doppler (TCD) for subarachnoid hemorrhage (SAH) ischemia assessment.
  • Evaluated SPECT for monitoring brain perfusion after interventions for arteriovenous malformations (AVMs) and aneurysms, and in intracranial hemorrhage (ICH).

    • Main Results:

    • SPECT accurately differentiates ischemic events from peri-ictal phenomena like Todd's paresis.
    • SPECT shows potential in predicting early stroke risk after TIAs and distinguishing stroke types.
    • Early SPECT imaging offers superior accuracy for ischemic areas in acute stroke compared to CT and MRI.
    • Large perfusion defects on SPECT correlate with increased risk of hemorrhagic complications or herniation.
    • SPECT conveniently documents reperfusion after thrombolysis.
    • Acetazolamide SPECT assesses vascular reserve in cerebrovascular stenosis.
    • SPECT aids in documenting ischemia post-SAH and evaluating perfusion changes after interventions or ICH.

    Conclusions:

    • Brain perfusion SPECT is a versatile tool in stroke management, offering diagnostic, prognostic, and therapeutic monitoring capabilities.
    • SPECT provides crucial information on brain perfusion, ischemia, and vascular reserve, often surpassing conventional imaging methods.
    • Its integration with other techniques like TCD enhances its clinical utility in complex cerebrovascular diseases.