Oral precancer: preventive and medical approaches to management

Leukoplakias are among the most common potentially malignant oral lesions. Some are idiopathic, others are related to habits such as tobacco and/or alcohol use. Medical management includes reducing or abandoning these habits, increasing the intake of fruit and vegetables in the diet, and possibly the use of active agents. Retinoids, carotenoids and topical cytotoxic agents show promise, and newer therapies are on the horizon.