The transoral transpalatal approach to the pituitary fossa
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Updated: Oct 24, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
A P Rose-Innes1, J H Oosthuizen
1Tygerberg Hospital, University of Stellenbosch Medical Faculty, Parow, Cape Town, South Africa.
Abstract:
Transpalatal trans-sphenoidal approaches to the sella turcica were described as early as 1900. Since the advent of effective trans-sphenoidal pituitary microsurgery in the 1960's, the sublabial transnasal approach became the most widely used. We reassessed the transoral transpalatal approach in 1978 and found the procedure to have distinct advantages over the transnasal operation. Between 1978 and 1992, 94 patients had transpalatal trans-sphenoidal explorations of the pituitary fossa at our institution. The detail of the operative technique, the results and the advantages are discussed.
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