Related Experiment Videos
SPECT imaging of fluorine-18
P K Leichner1, H T Morgan, K P Holdeman
1Department of Radiology, University of Nebraska Medical Center, Omaha 68198-1045, USA.
Unlabelled:
The objective of this work was to determine the potential clinical usefulness of SPECT to image 511-keV annihilation photons.
Methods:
A triple-headed gamma camera equipped with ultra-high-energy collimators was used to image 18F. Sensitivity measurements were carried out and the FWHM and FWTM were determined in air and for a unit-density scattering medium. Additionally, tomographic phantom studies were acquired to evaluate image quality.
Results:
The sensitivities of the three cameras were, for all practical purposes, identical. At a source-to-collimator distance of 100 mm, the FWHM and FWTM were 13 and 29 mm, respectively. A tomographic phantom study demonstrated that spheres with a diameter of 20 mm were well resolved when filled with 18F activity and placed inside a water-filled phantom.
Conclusion:
The triple-headed SPECT camera in this investigation is a practical means of acquiring tomographic 18F images. The reconstructed slices were of sufficient quality to be of value in some clinical studies.