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Conjoined twins

K M Pearce1, C P Mohler, D Housel

  • 1Department of Ob/Gyn, OUHSC, Oklahoma City 73190, USA.

The Journal of the Oklahoma State Medical Association
|June 1, 1995
PubMed
Summary
This summary is machine-generated.

Conjoined twins, or Siamese twins, occur when identical twins fuse during development. This rare condition results from the incomplete separation of a single fertilized egg.

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Area of Science:

  • Medical Science
  • Genetics
  • Developmental Biology

Background:

  • Conjoined twins, historically termed Siamese twins, represent a rare congenital anomaly.
  • The condition arises from the incomplete fission of a single zygote, leading to shared anatomy.

Observation:

  • The minimal diagnostic criterion for conjoined twins is the fusion of a portion of mononuclear or monozygotic twins.
  • This fusion can involve various shared organs and body parts.

Findings:

  • Conjoined twinning is fundamentally a failure of complete twin zygote separation.
  • The degree of fusion dictates the classification and potential surgical outcomes.

Implications:

  • Understanding the embryological basis is crucial for accurate diagnosis and management.
  • Advances in imaging and surgical techniques offer improved prognoses for select cases.