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Related Experiment Videos

Transmural eosinophilic gastroenteritis with ascites

P C McNabb, C R Fleming, J A Higgins

    Mayo Clinic Proceedings
    |February 1, 1979
    PubMed
    Summary
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    Eosinophilic gastroenteritis, a rare condition causing abdominal pain and ascites, was diagnosed in an atopic patient. Steroid treatment led to significant symptom improvement, highlighting its therapeutic potential.

    Area of Science:

    • Gastroenterology
    • Immunology
    • Pathology

    Background:

    • Eosinophilic gastroenteritis is a rare gastrointestinal disorder characterized by eosinophilic infiltration of the bowel wall.
    • Ascites is an uncommon but serious manifestation of eosinophilic gastroenteritis, particularly in adults.
    • Understanding the diagnostic challenges and treatment responses is crucial for managing this condition.

    Observation:

    • A case of an atopic patient presenting with recurrent abdominal pain, diarrhea, and ascites is detailed.
    • Diagnostic evaluation revealed dense eosinophilic infiltrates in the jejunal mucosa.
    • Eosinophilia was also detected in the ascitic fluid, supporting the diagnosis.

    Findings:

    • The patient was diagnosed with eosinophilic gastroenteritis involving transmural inflammation.

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  • The presence of eosinophilic infiltrates in the jejunum and ascitic fluid confirmed the diagnosis.
  • A significant clinical improvement was observed following steroid therapy.

    • Implications:

    • This case underscores the importance of considering eosinophilic gastroenteritis in patients with unexplained ascites and gastrointestinal symptoms.
    • Steroids appear to be an effective treatment modality for eosinophilic gastroenteritis with ascites.
    • Further review of similar cases can help elucidate the pathophysiology and optimize management strategies.