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Niacin for lipid disorders. Indications, effectiveness, and safety
1Division of Arteriosclerosis and Lipid Metabolism, Emory University School of Medicine, Atlanta, USA.
Abstract:
Niacin can be very effective and safe in lowering low-density lipoprotein cholesterol and triglyceride levels and also in increasing high-density lipoprotein cholesterol levels. In combination with other lipid-lowering drugs (eg, bile acid sequestrants), it has reduced the incidence of cardiovascular events and stopped the progression of coronary artery lesions. It may be the most cost-effective lipid-lowering agent currently available. At lower doses, sustained-release forms of niacin may also improve patient compliance.
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